Leading the way to a better tomorrow

Osiris Therapeutics, Inc. is a leading stem cell company focused on developing and marketing products to treat medical conditions in the inflammatory, orthopedic and cardiovascular areas. Osiris’ stem cell products have significant therapeutic potential because of their ability to regulate inflammation, promote tissue regeneration and prevent pathological scar formation.

The next revolution in medical care

Osiris Therapeutics is commercializing products from a readily available and non-controversial source – adult bone marrow. These stem cells have demonstrated the ability to repair different types of tissue and offer a very real opportunity to develop revolutionary new treatments for certain disease processes including inflammatory diseases, heart attacks, diabetes and arthritis.

Osiris’ technology is based on the pioneering work of Dr. Arnold Caplan and his colleagues at Case Western Reserve University. They showed that mesenchymal stem cells (MSCs) can engraft and selectively differentiate, based on the tissue environment, to such lineages as muscle, bone, cartilage, marrow stroma, tendon and fat. Due to their cellular origin and phenotype, these cells do not provoke an immune response, allowing for the development of products derived from unrelated human donors.