BIO4 ™

BIO4 ™ is a viable bone matrix containing endogenous bone forming cells including mesenchymal stem cells, osteoprogenitor cells, osteoblasts, osteoinductive and angiogenic growth factors. BIO4 possesses all four characteristics involved in bone repair and regeneration: osteoconductive, osteoinductive, osteogenic, and angiogenic. [1, 2] BIO4 ™ contains naturally occurring angiogenic growth factors, such as the vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF), which have been reported to be important for bone repair at sites of bone damage. [3,4]
  • Lot tested for the presence of VEGF (vascular endothelial growth factor) [1]
  • Lot tested for 70% cell viability post-thaw [1]
  • Contains on average at least 600,000 cells (endogenous bone forming cells including mesenchymal stem cells, osteoprogenitors and osteoblasts) per cc [1]
  • Ready to use out of the package; no decanting is required and thaws in 15 minutes
  • Differentiated handling compared to competition
stryker BIO4 ™ is manufactured and distributed by Osiris Therapeutics, Inc., and available through Stryker Corporation. For additional information or to order BIO4 ™ please contact Stryker customer service at (844) 550-5200. 

Learn More >